19 January 2026
EZH2 drives prostate cancer progression by regulating m6A RNA modification. By stabilizing FOXA1, EZH2 boosts YTHDF1 expression, enhancing translation of METTL14 and WTAP and increasing global m6A. Targeting this axis suppresses tumor growth.
30 September 2025
Discover how ribosome profiling is transforming translatomics, from its origins and cutting-edge methodologies to advanced bioinformatics and breakthrough applications in cancer, neurodegeneration, infectious diseases, and more.
22 September 2025
Researchers identified METTL5 as a key driver of immune resistance in ovarian cancer. By altering rRNA methylation and ATF4 translation, METTL5 suppresses ferroptosis, reducing response to immunotherapy. Targeting this axis may enhance ICB efficacy.
11 August 2025
Today, ribosomes are emerging as regulatory hubs that actively shape gene expression. Are you ready to uncover their hidden role and explore the technologies driving their discovery?
22 July 2025
SLE impairs oocyte development by disrupting translation linked to reduced ac4C modification. Using single-cell omics, researchers showed that boosting ac4C with nicotinamide improves oocyte quality in SLE mice—highlighting a promising fertility strategy
10 March 2025
mRNA localization is key for cell migration. Boraas et al identify hundreds of FA-enriched mRNAs & reveal that G3BP1 RNPs regulate FA function. By enhancing FA protein mobility & size, G3BP1 promotes cell speed—unveiling a new role beyond stress response.
