Immagina BioTechnology - The ribosome company

Products

RiboLace kit – improving ribosome profiling experiments

A novel method based on an original puromycin-containing molecule capable of isolating active ribosomes by means of an antibody-free and tag-free pull-down approach.

RiboNext 3PB (photo-active/ jeff-alkyne puromycin)

A UV-active alkyne analog of puromycin that binds to a network of proteins involved in ribosome function and activity (e.g. eEF1A, ENO1, GRP78).

RiboNext 3PC (photo-active/alkyne puromycin)

A UV-active alkyne analog of puromycin that efficiently binds to a network of proteins involved in ribosome function and activity

Click kit for UV-photoactive probes

The Click Chemistry Capture Kit provides all necessary reagents to covalently link specific 3Px probes by a Cu(I)-catalyzed azide-alkyne cycloaddition reaction (CuAAC) with the azide-PEG-biotin followed by pull-down of the tagged proteins by magnetic beads.

OPP (O-propargyl-puromycin)

OPP (O-propargyl-puromycin) is an alkyne analog of puromycin that is efficiently incorporated into newly translated proteins in complete methionine-containing media.

Neutravidin magnetic beads

Magnetic beads functionalized with neutravidin for the capture of biotinylated molecules or biotinylated antibodies. Quality controls are performed to ensure the maximum quality of our product.

Gold-coated nanoparticles and microparticles

Gold coated magnetic beads are obtained using a proprietary procedure. The particles show excellent chemical stability, magnetic properties and an intense surface plasmon resonance in the visible-NIR region.

Graphene magnetic beads

A magnetic core embedded in a hydrogel structure with Graphene Oxide or Reduced Graphene Oxide included in the matrix.

The Specialized Ribosome Technology Platform

New and better information for scientists, toward novel therapeutic strategies in cancer and congenital disorders

RP_RiboLace technology Based on an original puromycin-containing molecule capable of isolating active ribosomes by means of an antibody-free and tag-free pull-down approach. RP_RiboLace is fast, works reliably with low amounts of input material, and can be easily and rapidly applied both in vitro and in vivo, thereby generating a global snapshot of active ribosome footprints at single nucleotide resolution. Products: kit for RIBO-seq RiboMINATI technology (coming soon) Identification of a whole de novo synthesized proteome and translatome with the isolation of active ribosomes Products: kit for RNA-seq, kit for RIBO-seq, kit for immunoblotting, kit for LC-MS analysis RiboNext technology Small molecules that can efficiently interact with several proteins involved in translation, ribosome function, and RNA processing. Products: kit for RNA-seq, kit for LC-MS analysis Library prep for Ribo-seq and small RNA-seq with ONT and Illumina instruments (coming soon)

For customers

We are engaged with customers at every step of the way.

For investors

Pushing Forward With Collaborative R&D Models In Biotech.

Intellectual property

A platform of opportunities.

About us

The team leading IMMAGINA is composed by an experienced group of scientists, and c-level professionals, offering a mix of competencies that range from molecular biology, chemistry, nanotechnology, technology transfer, marketing and business development. Among them, members of TBA (http://t-ba.eu/), BAN-TN (http://www.iban.it/it/mappa-dei-ban) and I.E.C.T. (the Hermann Hauser - Institute for Entrepreneurship, http://www.iect.at/homepage/). The achievement of the many ambitious goals is sustained by the already accomplished R&D activities funded by both private and public stakeholders. Further, IMMAGINA relies on a series of partnerships already established to help the business and market development.

Mission

We deliver high-quality solutions to assess translational control of gene expression and translatome-associated biomarkers.

The Ribosome Company

Solutions

IMMAGINA designed, developed and commercialize a Specialized Ribosome Technology Platform to isolate and analyse active ribosomes and the associated RNA molecules that are being translated into proteins. The present platform includes several products and the following technologies: RP_RiboLace, RiboMINATI, RiboNext, Smart Beads and dedicated library-prep kits for Illumina and Oxford Nanopore sequencing instruments.

Vision

IMMAGINA ambition is to deliver smart solutions for truer gene expression analysis in research and hospital labs, to support life science worldwide. We are working to provide you with the best picture of gene expression. Because the message is only part of the story.

Team

Wants to join the startup company to help accomplish our mission?

Careers

Please send Curriculum vitae, a letter describing your interest and contact details of three references to info@immaginabiotech.com. We will contact you if a new position will be open.

News

Scientific publication – Cell Reports cover page – 11/2018

RiboLace on the cover! We thank our collaborators for contribution and support, and congratulations! see https://www.cell.com/cell-reports/fulltext/S2211-1247(18)31544-4

Scientific publication – IMMAGINA new tools on bioRxiv – 10/2018

Our preprint work describing new probes to sense the activity of protein synthesis and to capture associated RNA is now available on bioRxiv

Immagina Biotechnology has been featured by… (2017)

The Next Tech – World Cancer Day And local media are sometimes important to help the local business community…

New patent / Novel agarose-based graphene beads and uses thereof – 09/2017

We announce a new patent describing new tools for specific catalytic reactions, adsorption and separation of molecules. New achievements in chemistry, biotechnology and environmental fields are now possible!

Scientific Publication – 08/2017

Our first paper reporting the basic of our RiboLace technology Active ribosome profiling with RiboLace is now public available on bioRxiv. The paper describes a novel method based on an original puromycin-containing molecule capable of isolating active ribosomes by means of an antibody-free and tag-free pull-down approach. RiboLace is fast, works reliably with low amounts of input material, […]

Our beads are now on the market! – 03.2017

see Beads Galaxy

Contact us

Immagina BioTechnology s.r.l - P.IVA/Vat n°: 02335400228

Headquarter: via alla Cascata 56/c, 38123 - Povo, Trento, Italy
Operative support: Via Sommarive 18, 38123 Trento, Italy - tel: 0039 0461.312018

Immagina performs the recruitment through its website. If you wish to be considered you are welcome to submit your details, using the contact form.