CircAID-p-seq for Oxford Nanopore Technologies

Selective sequencing of short RNAs bearing a 3’P or 2′,3′ cP end
Quick (1-day) high quality library preparation
No library PCR amplification bias
Suitable for RNA footprinting, Ribosome Profiling and transcriptome analysis.

AHARIBO for de novo proteome

Isolation of nascent peptides associated with active polyribosomes
Easy and quick pull-down approach
Parallel RNA and protein analysis if combines to AHARIBO for RNA
Suitable for downstream mass spec. and Western blot analysis.

AHARIBO for RNA

Isolation of active polyribosomes and associated RNAs
Easy and quick pull-down approach
Parallel RNA and protein analysis if combines to AHARIBO for proteome
Suitable for downstream RNAseq, qPCR and Ribo-seq.

RiboLace Ribo-Seq kit library prep

Isolation of active ribosomes
Antibody-free and tag-free pull-down approach
Input material 40x less than standard Ribosome Profiling protocols
Optimized protocol for library preparation

The Specialized Ribosome Technology Platform

New and better information for scientists, toward novel therapeutic strategies in cancer and congenital disorders. We design, we produce and we provide research tools for gene expression analysis at the ribosomal level

For customers

We are engaged with customers at every step of the way.

For investors

Pushing Forward With Collaborative R&D Models In Biotech.

Intellectual property

A platform of opportunities.

Products

RiboLace kit – improving ribosome profiling experiments

A novel method based on an original puromycin-containing molecule capable of isolating active ribosomes by means of an antibody-free and tag-free pull-down approach.

Library Prep for ribosome profiling

Library prep for ribosome profiling kit is used to prepare libraries starting from Ribosome Protected Fragments (RPFs) isolated using RiboLace Ribo-Seq or other protocols.

CircAID-p-seq for Oxford Nanopore Technologies

CircAID-p-seq kit is designed for quick (1-day) high-quality library preparation for short RNAs bearing a 3’-phosphate/2’,3’-cyclic phosphate compatible with Oxford Nanopore platform.

Small molecules for monitoring protein synthesis

Tools for monitoring protein synthesis and studying translation on the protein-exposed ribosome surface in research, industrial and medical fields.

AHARIBO RNA

Specific for the analysis of translatome through the isolation of active ribosomes

AHARIBO Protein

AHARIBO for de novo proteome analysis is dedicated to the analysis of newly synthesized proteins.

Micro and nanoparticles for biological applications

A selection of micro and nanoparticles based on silica, gold, graphene, and hydrogels for applications of in biology and biotechnology.

About us

IMMAGINA BioTechnology s.r.l (The Ribosome Company) is a company operating in the MedTech sector of Genomics, Proteomics and Enabling Technology, that is incubated in the Laboratory for Biomolecular Sequence and Structure Analysis for Health in Trento (Italy). Our mission is to deliver high-quality solutions to assess translational control of gene expression and translatome-associated biomarkers. IMMAGINA was founded in 2014, when the founder (Dr. Massimiliano Clamer) started to develop RiboLace^TM, the only technology that enable the capture of active ribosomes. RiboLace is on the market from November 2018. Starting from 2016, thanks to the levering investments from private investors (of whom the most relevant one is BAN/TN, TBA network and the Herman Hauser Investment) and the recruitment of new experienced scientists, two new technologies for translatome analysis (AHARIBO^TM and circAID-p-seq^TM) were developed and finally launched on the market at the end of 2019. IMMAGINA offers a platform of products with the potential to accelerate the path toward the discovery of novel therapeutic strategies.

Mission

We deliver high-quality solutions to assess translational control of gene expression and translatome-associated biomarkers.

The Ribosome Company

Solutions

IMMAGINA designed, developed and commercialize a Platform Technology focused on Ribosome to isolate and analyse active ribosomes and the associated RNA molecules

Vision

IMMAGINA ambition is to deliver smart solutions for truer gene expression analysis in research and pharma labs, to support life science worldwide. We are working to provide you with the best picture of gene expression. Because the message is only part of the story.

Team

Wants to join the startup company to help accomplish our mission?

Careers

We are looking for highly motivated scientists. Open positions: IMMAGINA Position_ID007 and position IMMAGINA Position_ID008

News

One-shot analysis of translated mammalian lncRNAs with AHARIBO

We present AHARIBO, a new method for the detection of lncRNAs either untranslated, but associated with ribosomes, or encoding small peptides.

[cit] Article Published: 02 March 2020 SRSF7 maintains its homeostasis through the expression of Split-ORFs and nuclear body assembly (Nature Structural & Molecular Biology) – 2020

[cit] Article Published: 02 March 2020 SRSF7 maintains its homeostasis through the expression of Split-ORFs and nuclear body assembly (Nature Structural & Molecular Biology)- 2020

In February 2020 IMMAGINA BioTechnology raised 1M Euro from existing investors and new, undisclosed EU-based investors. The Company has raised about 2M Euro to date

In February 2020 IMMAGINA raised 1 M Euro from existing investors and new, undisclosed EU-based investors. The Company has raised about 2 M Euro to date

Graphene oxide nanocomposite magnetic microbeads for the biotech sector – 2020

New magnetic agarose based graphene microbeads with enhanced physical–chemical properties for biochemical applications.

Active Ribosome Profiling with RiboLace – 2018

Ribolace: A novel method based on an innovative puromycin analogue capable of isolating ribosome in active translation.

SMN-primed ribosomes modulate the translation of transcripts related to Spinal Muscular Atrophy – 2019

RiboLace to study Spinal Muscular Atrophy.
SMN-primed ribosomes modulate the translation of transcripts related to Spinal Muscular Atrophy