RiboMINATI

Isolation of active polyribosomes, associated RNAs and nascent peptides
Easy and quick pull-down approach
Parallel RNA and protein analysis
Suitable for downstream RNAseq, qPCR, Mass Spectrometry and Western Blot analyses

RiboLace Ribo-Seq kit library prep

Isolation of active ribosomes
Antibody-free and tag-free pull-down approach
Input material 40x less than standard Ribosome Profiling protocols
Optimized protocol for library preparation

IMMAGINA BioTechnology at London Calling 2019

IMMAGINA BioTechnology presented at Oxford Nanopore London Calling 2019.

A short-RNA library prep kit for the ONT platform coming soon…stay tuned!!!!!

The Specialized Ribosome Technology Platform

New and better information for scientists, toward novel therapeutic strategies in cancer and congenital disorders. We design, we produce and we provide research tools for gene expression analysis at the ribosomal level

For customers

We are engaged with customers at every step of the way.

For investors

Pushing Forward With Collaborative R&D Models In Biotech.

Intellectual property

A platform of opportunities.

Products

RiboMINATI – for parallel RNA sequencing and protein analysis

Specific for the identification of a whole de novo synthesized proteome (proteins) and translatome (RNAs) with the isolation of active ribosomes

RiboLace kit – improving ribosome profiling experiments

A novel method based on an original puromycin-containing molecule capable of isolating active ribosomes by means of an antibody-free and tag-free pull-down approach.

Small molecules for monitoring protein synthesis

Tools for monitoring protein synthesis and studying translation on the protein-exposed ribosome surface in research, industrial and medical fields.

Micro and nanoparticles for biological applications

A selection of micro and nanoparticles based on silica, gold, graphene, and hydrogels for applications of in biology and biotechnology.

About us

The team leading IMMAGINA is composed by an experienced group of scientists, and c-level professionals, offering a mix of competencies that range from molecular biology, chemistry, nanotechnology, technology transfer, marketing and business development. Among them, members of TBA (http://t-ba.eu/), BAN-TN (http://www.iban.it/it/mappa-dei-ban) and I.E.C.T. (the Hermann Hauser - Institute for Entrepreneurship, http://www.iect.at/homepage/). The achievement of the many ambitious goals is sustained by the already accomplished R&D activities funded by both private and public stakeholders. Further, IMMAGINA relies on a series of partnerships already established to help the business and market development.

Mission

We deliver high-quality solutions to assess translational control of gene expression and translatome-associated biomarkers.

The Ribosome Company

Solutions

IMMAGINA designed, developed and commercialize a Specialized Ribosome Technology Platform to isolate and analyse active ribosomes and the associated RNA molecules that are being translated into proteins. The present platform includes several products and the following technologies: RP_RiboLace, RiboMINATI, RiboNext, Smart Beads and dedicated library-prep kits for Illumina and Oxford Nanopore sequencing instruments.

Vision

IMMAGINA ambition is to deliver smart solutions for truer gene expression analysis in research and hospital labs, to support life science worldwide. We are working to provide you with the best picture of gene expression. Because the message is only part of the story.

Team

Wants to join the startup company to help accomplish our mission?

Careers

We are looking for a highly motivated Computational biologist to work on RNA-seq data Please send Curriculum vitae, a letter describing your interest and contact details of three references to info@immaginabiotech.com. We will contact you if a new position will be open.

News

Scientific publication – ACS Omega – 06/2019

Targeting Translation Activity at the Ribosome Interface with UV-Active Small Molecules UV-active puromycin derivatives that cannot be transferred to the growing peptide chain can be used to study protein synthesis activity and label productive ribosome-associated protein (http://doi.org/10.1021/acsomega.9b00366). Compounds available in the store online

Scientific publication – Cell Reports cover page – 11/2018

RiboLace on the cover! We thank our collaborators for contribution and support, and congratulations! see https://www.cell.com/cell-reports/fulltext/S2211-1247(18)31544-4

Scientific publication – IMMAGINA new tools on bioRxiv – 10/2018

Our preprint work describing new probes to sense the activity of protein synthesis and to capture associated RNA is now available on bioRxiv

Immagina Biotechnology has been featured by… (2017)

The Next Tech – World Cancer Day And local media are sometimes important to help the local business community…

New patent / Novel agarose-based graphene beads and uses thereof – 09/2017

We announce a new patent describing new tools for specific catalytic reactions, adsorption and separation of molecules. New achievements in chemistry, biotechnology and environmental fields are now possible!

Scientific Publication – 08/2017

Our first paper reporting the basic of our RiboLace technology Active ribosome profiling with RiboLace is now public available on bioRxiv. The paper describes a novel method based on an original puromycin-containing molecule capable of isolating active ribosomes by means of an antibody-free and tag-free pull-down approach. RiboLace is fast, works reliably with low amounts of input material, […]

Contact us

Immagina BioTechnology s.r.l - P.IVA/Vat n°: 02335400228

Headquarter: via alla Cascata 56/c, 38123 - Povo, Trento, Italy
Operative support: Via Sommarive 18, 38123 Trento, Italy - tel: 0039 0461.312018

Immagina performs the recruitment through its website. If you wish to be considered you are welcome to submit your details, using the contact form.