CircAID-p-seq for Oxford Nanopore Technologies


  • Selective sequencing of short RNAs bearing a 3’P  or 2′,3′ cP end
  • Quick (1-day) high quality library preparation
  • No library PCR amplification bias
  • Suitable for RNA footprinting, Ribosome Profiling and transcriptome analysis.


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AHARIBO for de novo proteome

  • Isolation of nascent peptides associated with active polyribosomes
  • Easy and quick pull-down approach
  • Parallel RNA and protein analysis if combines to AHARIBO for RNA
  • Suitable for downstream mass spec. and Western blot analysis.

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  • Isolation of active polyribosomes and associated RNAs 
  • Easy and quick pull-down approach
  • Parallel RNA and protein analysis if combines with AHARIBO for proteome
  • Suitable for downstream RNAseq and qPCR

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RiboLace Ribo-Seq kit library prep

  • Isolation of active ribosomes
  • Antibody-free and tag-free pull-down approach
  • Input material 40x less than standard Ribosome Profiling protocols
  • Optimized protocol for library preparation

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The Specialized Ribosome Technology Platform

New and better information for scientists, toward novel therapeutic strategies in cancer and congenital disorders. We design, we produce and we provide research tools for gene expression analysis at the ribosomal level 


For customers

We are engaged with customers at every step of the way.

For investors

Pushing Forward With Collaborative R&D Models In Biotech.

Intellectual property

A platform of opportunities.


RiboLace kit – improving ribosome profiling experiments

A novel method based on an original puromycin-containing molecule capable of isolating active ribosomes by means of an antibody-free and tag-free pull-down approach.

Library Prep for ribosome profiling

Library prep for ribosome profiling kit is used to prepare libraries starting from Ribosome Protected Fragments (RPFs) isolated using RiboLace Ribo-Seq or other protocols.

CircAID-p-seq for Oxford Nanopore Technologies

CircAID-p-seq kit is designed for quick (1-day) high-quality library preparation for short RNAs bearing a 3’-phosphate/2’,3’-cyclic phosphate compatible with Oxford Nanopore platform.

Small molecules for monitoring protein synthesis

Tools for monitoring protein synthesis and studying translation on the protein-exposed ribosome surface in research, industrial and medical fields.


Specific for the analysis of translatome through the isolation of active ribosomes


AHARIBO for de novo proteome analysis is dedicated to the analysis of newly synthesized proteins

Micro and nanoparticles for biological applications

A selection of micro and nanoparticles based on silica, gold, graphene, and hydrogels for applications of in biology and biotechnology.

About us

IMMAGINA BioTechnology s.r.l (The Ribosome Company) is a company operating in the MedTech sector of Genomics, Proteomics and Enabling Technology, that is incubated in the Laboratory for Biomolecular Sequence and Structure Analysis for Health in Trento (Italy). Our mission is to deliver high-quality solutions to assess translational control of gene expression and translatome-associated biomarkers. IMMAGINA was founded in 2014, when the founders started to develop RiboLaceTM, the only technology that enables the capture of active ribosomes. RiboLace is on the market from November 2018. Starting from 2016, thanks to the levering investments from private investors (of whom the most relevant one is BAN/TN, TBA network and the Herman Hauser Investment) and the recruitment of new experienced scientists, two new technologies for translatome analysis (AHARIBOTM and circAID-p-seqTM) were developed and finally launched on the market at the end of 2019. IMMAGINA offers a platform of products with the potential to accelerate the path toward the discovery of novel therapeutic strategies.


We deliver high-quality solutions to assess translational control of gene expression and translatome-associated biomarkers.

The Ribosome Company


IMMAGINA designed, developed and commercialize a Platform Technology focused on Ribosome to isolate and analyse active ribosomes and the associated RNA molecules


IMMAGINA ambition is to deliver smart solutions for truer gene expression analysis in research and pharma labs, to support life science worldwide. We are working to provide you with the best picture of gene expression. Because the message is only part of the story.

Supporters & partners


Wants to join the startup company to help accomplish our mission?


The European Training Network named ROPES (ROle of EPitranscriptomics in DiseasES) has been granted in the framework of the Horizon 2020 Marie Skłodowska-Curie Action for Innovative Training Network (ITN). The project aims to unravel the role of epitranscriptomics in diseases and to exploit it for novel therapies. ROPES, awarded with 3M € from the European Commission, will start on December 2020 and will recruit Early Stage Researchers to perform innovative research projects in cooperation with leading universities in Europe and the United States of America.

ROPES will recruit twelve early-stage researchers, one of which at IMMAGINA BioTechnology Srl. More info and application here: Horizon 2020 - Marie Sklodowska-Curie Actions ROPES position in IMMAGINA


New scientific publication: Phospho-RNA sequencing with CircAID-p-seq

[Dec 2020] IMMAGINA BioTechnology presents, together with its partners at Genexa, TB-seq, the Institute for Biophysics at CNR Trento and the Edinburgh Medical School, Biomedical Sciences a preprint publication featuring the first commercially available Phospho RNA sequencing kit called circAID-pseq (CIRCular Amplification and IDentification of short 3′ Phosphate RNA SEQuences). Press release / Go to […]

Immagina Biotech and Tri-I Biotech announce distribution agreement

Immagina Biotech is very pleased to announce the appointment of Tri-I Biotech Inc as its official distributor in Taiwan to further expand and grow its business operations in Asia.

Nature Pubblication: SMN-primed ribosomes modulate the translation of transcripts related to Spinal Muscular Atrophy

RiboLace to study Spinal Muscular Atrophy.
SMN-primed ribosomes modulate the translation of transcripts related to Spinal Muscular Atrophy

Winners of the Immagina Ribo-Omics Grant Challenge 2020.

We are excited to share the winners of the
Immagina Ribo-Omics Grant Challenge 2020.

Online webinar: Spinal Muscular Atrophy: lost in translation?

IMMAGINA BIOTECHNOLOGY and TomaLab are excited to host a series of free live scientific webinars. During the webinars, prestigious speakers will present their recent researches carried out by the use of IMMAGINA BIOTECH products for the study of translational control of gene expression and diseases.

Officially announcing the collaboration between IMMAGINA Biotechnology and Genexa!

We are working together to develop a powerful data analysis tool for the only product available for 3’ phospho-RNA sequencing with ONT platform, CircAID-p-seq! Genexa is a service provider for bioinformatic analyses based in Zurich, Switzerland. Genexa’s services are centered around the analysis of third- and next-generation genomics data and the development of novel data […]

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Immagina performs the recruitment through its website. If you wish to be considered you are welcome to submit your details, using the contact form.

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