EZH2 drives prostate cancer progression by regulating m6A RNA modification. By stabilizing FOXA1, EZH2 boosts YTHDF1 expression, enhancing translation of METTL14 and WTAP and increasing global m6A. Targeting this axis suppresses tumor growth.
Miluzio et al. reveal that eIF6 phosphorylation is essential for ribosome recycling after termination. Cellular stress disrupts this process, causing ribosomes to stall at stop codons.