26 March 2024
AHARIBO sheds light on hidden functions of lncRNAs. It reveals ribosome-interacting lncRNAs and those producing small proteins in stem cells. This unveils functions beyond simple transcription for hundreds of lncRNAs.
26 March 2024
Non-AUG start codons are used more than expected, leading to diverse protein forms with potentially new functions. New methods reveal these "alternative translation initiation sites" (aTIS).
26 March 2024
A mouse model for MHC-I antigens isolation from specific cells in tumors. Antigen expression doesn't always match mRNA levels, suggesting new cancer vaccine targets & need for better prediction methods. Model works in various tissues & diseases.
20 March 2024
Simone Sidoli, Assistant Professor and PI of Sidoli Lab at the Albert Einstein College of Medicine, Ullmann Research Center for Health Sciences in New York about his research in proteomics and specifically de novo protein synthesis
20 March 2024
Alex Jaeger, Postdoctoral Fellow at the Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology, talks about translation analysis and its role in his cancer research
19 March 2024
Transcriptome poorly predicts protein levels. New methods (Polysome Profiling, Ribosome Profiling) study ribosome-mRNA interactions to decipher translational control of gene expression.
