Short reviews

19 March 2024

Proteo-translatomics: when proteomic and translatomics merge together

Protein expression at a given time determines the cellular states. mRNA and protein expression are tightly linked and finely regulated by transcripts and proteins production/degradation. A multitude of studies using quantitative proteomics in conjugation with transcriptomic has shown that globally there is a poor correlation between mRNA and protein levels in various biological systems. It has become evident that translational control appears to be critical in determining the steady-state levels of most cellular proteins...