Our platform

Our technology platform pioneers the isolation and characterization of active ribosomes and associated coding and noncoding RNAs. We propel biomedical knowledge by enabling researchers to investigate translational vulnerabilities that may contribute to disease development or therapeutic response. 

A promising source

The ribosome stands as a promising source of potential drug targets and RNA-based drug modulators, embodying key mechanisms crucial for ribosome homeostasis.

These encompass:

  • ribosome synthesis 
  • translational cycle regulation in both canonical and alternative translation
  • induction of ribosome pausing
  • quality control process implementation for retrieving or rescuing translationally stalled ribosomes
  • orchestration of ribosome heterogeneity and specialized translation