Global brain transduction of the instability-prone Mecp2 transgene by systemic AAV-PHP.eB administration is both safe and effective in protecting male and female Mecp2 mutant mice from the RTT disease phenotype
Ribosome profiling enables codon resolution analysis of mRNA translation.
New methods based on ribosome profiling provide novel insights into translational control.
Many tools are developed to facilitate the analysis of ribosome profiling data.
uORF-Tools is designed for intuitive use and requires only limited computing times
and resources
Our preprint work describing new probes to sense the activity of protein synthesis and to capture associated RNA is now available on bioRxiv
The Next Tech – World Cancer Day And local media are sometimes important to help the local business community…
We announce a new patent describing new tools for specific catalytic reactions, adsorption and separation of molecules. New achievements in chemistry, biotechnology and environmental fields are now possible!
Our first paper reporting the basic of our RiboLace technology Active ribosome profiling with RiboLace is now public available on bioRxiv. The paper describes a novel method based on an original puromycin-containing molecule capable of isolating active ribosomes by means of an antibody-free and tag-free pull-down approach. RiboLace is fast, works reliably with low amounts of input material, […]
see Beads Galaxy
Viero’s Lab published In vivo translatome profiling reveals early defects in ribosome biology underlying SMA pathogenesis in bioRxivpreprint. The results described suggest that neuronal tissues and cells are particularly sensitive to perturbations in translation during SMA, and identify ribosome biology as an important, yet largely neglected, factor in motor neuron degeneration
FINSMES http://www.finsmes.com/2016/11/immagina-biotechnology-raises-e480k-in-funding.html Immagina Biotechnology has developed a patented technology, called RiboLace, which enables users to better understand how cells works, with applications in the fiels of personalized medicine research. The company is currently working in advancing studies in the field of cancer and neurodegenerative diseases and its products can be acquired by research labs and […]